The licensee shall ensure all necessary security arrangements in the manufacturing premises as may be specified by the issuing authority.
1[43. Advance notice for cessation and recommencement of manufacture.
(1) The licencee shall give at least one month's notice in writing to the issuing authority before he ceases to manufacture the drug for any reasons whatsoever:
2[Provided that the notice referred to in this sub-rule shall not apply in case the cessation of manufacture is on account of unforeseen circumstances beyond the control of the licencee. I
(2) The licencee shall give at least fifteen days notice in writing to the issuing authority prior to the date of recommencement of manufacture of the drug after cessation of manufacture of the drug as mentioned at sub-rule (1).)