Xe) "Experiment" means any programme or project involvin fOr the acquisition of knowledge of a biological, physiol i physical or chemical nature; and includes the use of animal(s) of reagents and products such as antigens and antibodies, roi tfsting activity and establishment of transgenic stocks, for the or prolonging life or alleviating suffering or significant gains people of the country or for combating any disease whether of animals;'
use of animal(s) I, ethoiogical, n the production ine diagnostics, rpose of saving n well being for human beings or 3; In rule 9 of the said rules, -
(1) after clause (b), the following clause shall be inserted, namely:- "(Jbb) animals lowest on the phylogenetic scale which may valid results should be first considered for any experimental experiment should be designed using minimum number of i statistically valid results at 95% degree of confidence:
live scientifically procedure and the animals to give experiments on ustification must
Provided that replacement alternatives not involving animals should be given due and full consideration and sound be provided in case alternatives, though available, are not used;
(2) after clause (c), the following clause shall be inserted, namely:
''(cc) (i) personnel using experimental animal(s) shall be responsible for the welfare of animal(s) during their use in experiments; I
(ii) investigators shall be responsible for the aftercare knd rehabilitation Of animal(s) after experimentation, and shall not euthanise animal(s) except in situations as defined in clause (ff);
[VFTII—lsFg3(ii)] ÎRrt °ET <\MHH : aTOT̂ RPI 7
(iii) costs of aftercare and rehabilitation of animal(s) after experimentation shall be made part of research costs and shall be scaled in positive correlation with the level of costs involved in such aftercare and rehabilitation of the animal(s);
(iv) rehabilitation treatment of an animal after experimentation shall extend till the point the animal is able to resume a normal existence by providing a lump-sum amount as costs for rehabilitation and care of such animal to cover its entire statistical expected life span; and
(v) the establishment undertaking experiments or duly licensed and authorised animal welfare organization under the control of the Committee may, on payment of lump-sum amount, undertake rehabilitation of animals;";
(3) after clause (f), the following clause shall be inserted, namely:- "(ff) the following parameters shall be adopted for application of euthanasia, namely:-
(i) when the animal is paralyzed and is not able to perform its natural functions or it becomes incapable of independent locomotion or it can no longer perceive the environment in an intelligible manner; or
(ii) if during the course of experimental procedure the animal has been left with a recurring pain wherein the animal exhibits obvious signs of pain and suffering; or
(iii) where the non-termination of the life of the experimental animal will be life threatening to human beings or other animals;".
4. In rule 10 of the said rules, -
(1) for clause (b), the following clause shall be substituted, namely:- "(b) (i) an establishment shall acquire animal(s) for experiments from registered breeders only;
(ii) in case of non-availability of animal(s) from registered breeders, the animaKs) may be procured from alternate legal sources;
THE GAZETTE OF INDIA: EXTRAORDINARY lefaal [PART II—SEc.3(ii)]
(iii) in case the animal is procured from the alternate legal sources, the sarne shall be procured after taking written permission froin the authority competent under the law for the time being in force, to give such permission; and
(iv) the establishment procuring such animal shall maintain a record in this regard and shall produce the same before the Committee, whenever required;"; | breeder or from animals may be
(2) for clause (e), the following clause shall be substituted, namely:- "(p) In case an animal is not available from a registered alternate legal sources within the country, genetically defined imported with permission of Directorate General of Foreign Tradi a
Provided that the condition of non-availability within the count! y shall not apply for laboratory bred rats and mice of genetically defined strains;".